COVID19 Safety Alert

History of Miscarriages, Now 9 Weeks Pregnant: Continue Progesterone Supplement (Crinone) ?

Question:

I'm from the U.S. After a long struggle with secondary infertility and 2 miscarriages, I am pregnant again, 9 weeks along. I'm on supplemental progesterone, Crinone 8% once a day. When can I feel okay about stopping the Crinone? I was supposed to see my doctor in 2 days, but he experienced a family tragedy, and I'm not sure when he'll be back. I think he had talked about stopping the Crinone at 9 or 10 weeks, but I was going to confirm that with him at my appointment, and I have no way of asking now.

Thank you for your time. M. from the U.S.

Answer:

Hello M. from the U.S.,

With your history of two miscarriages, I will usually be very conservative and continue the progesterone until 12 weeks gestational age.  However, medically, it would be okay to stop at 10 weeks.  By then, the placenta should be fully functional and providing all the hormone necessary to maintain the pregnancy.

Good luck!

Dr. Edward J. Ramirez, M.D., FACOG

Executive Medical Director

The Fertility and Gynecology Center

Monterey Bay IVF Program

www.montereybayivf.com 

Monterey, California, U.S.A.

**For my readers who are unfamiliar with the use of progesterone to support a pregnancy, here are some additional facts: "Progesterone is essential for the normal functioning of the reproductive system. After ovulation, the corpus luteum (which is the empty follicle from which the egg was released) produces progesterone, which acts on the womb lining and causes it to thicken in preparation for a fertilized egg to implant. This is known as the luteal phase of the menstrual cycle. If an egg implants successfully into the womb, the corpus luteum continues to produce progesterone to maintain the pregnancy until the placenta develops fully. The placenta produces increasing amounts of progesterone until it is fully developed, when it then takes over the production of progesterone to continue to support the pregnancy.

In some women, insufficient progesterone is produced during the luteal phase and this causes problems with implantation of fertilized eggs into the womb lining and maintaining a pregnancy in the early stages. Crinone vaginal gel is used to treat this hormone deficiency. One applicatorful is inserted into the vagina every day, starting either one day after ovulation is known to have occurred, or on day 18 to 21 of the woman's cycle. (Day one is the first day of your period.) The gel is usually continued until the placenta is producing enough progesterone to support the pregnancy.
Crinone vaginal gel is also used to support pregnancy in women having in vitro fertilization (IVF). In this case the gel is used daily, starting after the embryo has been transferred into the womb, for the first 30 days of confirmed pregnancy." www.netdoctor.co.uk/pregnancy/medicines/crinone.html

You Might Also Enjoy...

My Pap Smear Was Abnormal - Now What?

A Pap smear, or Pap test, is a screening test recommended for women ages 21-65 to detect early signs of cervical cancer. Abnormal results can be scary, but there are a few things you need to know.

5 Common Myths About Infertility

Infertility can send you on a search for answers. Unfortunately, there are a lot of wrong answers out there. This post sets the record straight regarding five common myths about infertility.

Is Preimplantation Genetic Testing?

Couples who have chosen in vitro fertilization are taking a big step toward becoming parents. Preimplantation genetic testing is an important part of the process and can ensure your embryo is healthy before being transferred to the uterus.

5 Symptoms of Endometriosis

Are you experiencing uncomfortable symptoms related to your menstrual cycle? Between 2% and 10% of American women have endometriosis, which can cause numerous symptoms.

COVID-19 Update and Measures Taken

Dear patients, Update: As of April 6, 2020 our clinic will be operating on minimum staff. Dr. Ramirez has been deployed with his U.S. Army medical reserve unit to the East Coast to assist in supporting a field hospital.